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Bioprinted Human Tissue

Organovo’s proprietary bioprinting platform captures the unique synergistic potential of engineering and biology to enable the reproducible, automated creation of living human tissues that mimic the form and function of native tissues in the body. Genomics and proteomics have revolutionized research through the creation of highly reproducible tools for studying the genome and proteome. Organovo seeks to create a highly reproducible, dynamic 3D platform for Organomics ™, the study of living organs in vitro. Our 3D bioprinted human tissues are constructed with precision from tiny building blocks made of living human cells, using a process that translates tissue-specific geometries and cellular components into 3D designs that can be executed by an Organovo NovoGen Bioprinter™. Once built, the bioprinted tissues share many key features with native tissue, including tissue-like cellular density, presence of multiple cell types, and the development of key architectural and functional features associated with the target native tissue.

Organovo’s 3D human tissues offer many advantages over standard cell-culture platforms due to the fact that three-dimensionality is achieved without dependence on biomaterial or scaffold components that would not be found in native tissues.

Organovo's scientific founder, Gabor Forgacs, presents on bioprinting at TEDMED.